diff --git a/include/sway/commands.h b/include/sway/commands.h
index 7ff3b651..d994ae9b 100644
--- a/include/sway/commands.h
+++ b/include/sway/commands.h
@@ -246,6 +246,7 @@ sway_cmd input_cmd_events;
 sway_cmd input_cmd_left_handed;
 sway_cmd input_cmd_map_from_region;
 sway_cmd input_cmd_map_to_output;
+sway_cmd input_cmd_map_to_region;
 sway_cmd input_cmd_middle_emulation;
 sway_cmd input_cmd_natural_scroll;
 sway_cmd input_cmd_pointer_accel;
diff --git a/include/sway/config.h b/include/sway/config.h
index 8c93c20d..0a010c6d 100644
--- a/include/sway/config.h
+++ b/include/sway/config.h
@@ -148,6 +148,7 @@ struct input_config {
 
 	struct input_config_mapped_from_region *mapped_from_region;
 	char *mapped_to_output;
+	struct wlr_box *mapped_to_region;
 
 	bool capturable;
 	struct wlr_box region;
diff --git a/sway/commands/input.c b/sway/commands/input.c
index 2289ede5..a11ad79a 100644
--- a/sway/commands/input.c
+++ b/sway/commands/input.c
@@ -18,6 +18,7 @@ static struct cmd_handler input_handlers[] = {
 	{ "left_handed", input_cmd_left_handed },
 	{ "map_from_region", input_cmd_map_from_region },
 	{ "map_to_output", input_cmd_map_to_output },
+	{ "map_to_region", input_cmd_map_to_region },
 	{ "middle_emulation", input_cmd_middle_emulation },
 	{ "natural_scroll", input_cmd_natural_scroll },
 	{ "pointer_accel", input_cmd_pointer_accel },
diff --git a/sway/commands/input/map_to_region.c b/sway/commands/input/map_to_region.c
new file mode 100644
index 00000000..e0b69ed5
--- /dev/null
+++ b/sway/commands/input/map_to_region.c
@@ -0,0 +1,56 @@
+#define _POSIX_C_SOURCE 200809L
+#include <stdlib.h>
+#include <string.h>
+#include <wlr/types/wlr_box.h>
+#include "sway/commands.h"
+#include "sway/config.h"
+
+struct cmd_results *input_cmd_map_to_region(int argc, char **argv) {
+	struct cmd_results *error = NULL;
+	if ((error = checkarg(argc, "map_to_region", EXPECTED_EQUAL_TO, 4))) {
+		return error;
+	}
+	struct input_config *ic = config->handler_context.input_config;
+	if (!ic) {
+		return cmd_results_new(CMD_FAILURE, "No input device defined");
+	}
+
+	// This is used to clear the current output mapping.
+	ic->mapped_to_output = strdup("");
+
+	ic->mapped_to_region = calloc(1, sizeof(struct wlr_box));
+
+	const char *errstr;
+	char *end;
+
+	ic->mapped_to_region->x = strtol(argv[0], &end, 10);
+	if (end[0] != '\0') {
+		errstr = "Invalid X coordinate";
+		goto error;
+	}
+
+	ic->mapped_to_region->y = strtol(argv[1], &end, 10);
+	if (end[0] != '\0') {
+		errstr = "Invalid Y coordinate";
+		goto error;
+	}
+
+	ic->mapped_to_region->width = strtol(argv[2], &end, 10);
+	if (end[0] != '\0' || ic->mapped_to_region->width < 1) {
+		errstr = "Invalid width";
+		goto error;
+	}
+
+	ic->mapped_to_region->height = strtol(argv[3], &end, 10);
+	if (end[0] != '\0' || ic->mapped_to_region->height < 1) {
+		errstr = "Invalid height";
+		goto error;
+	}
+
+	return cmd_results_new(CMD_SUCCESS, NULL);
+
+error:
+	free(ic->mapped_to_region);
+	ic->mapped_to_region = NULL;
+	return cmd_results_new(CMD_FAILURE, errstr);
+}
diff --git a/sway/config/input.c b/sway/config/input.c
index ad4a64ee..294ed08f 100644
--- a/sway/config/input.c
+++ b/sway/config/input.c
@@ -138,6 +138,13 @@ void merge_input_config(struct input_config *dst, struct input_config *src) {
 		free(dst->mapped_to_output);
 		dst->mapped_to_output = strdup(src->mapped_to_output);
 	}
+	if (src->mapped_to_region) {
+		free(dst->mapped_to_region);
+		dst->mapped_to_region =
+			malloc(sizeof(struct wlr_box));
+		memcpy(dst->mapped_to_region, src->mapped_to_region,
+			sizeof(struct wlr_box));
+	}
 	if (src->calibration_matrix.configured) {
 		dst->calibration_matrix.configured = src->calibration_matrix.configured;
 		memcpy(dst->calibration_matrix.matrix, src->calibration_matrix.matrix,
@@ -323,6 +330,7 @@ void free_input_config(struct input_config *ic) {
 	free(ic->xkb_variant);
 	free(ic->mapped_from_region);
 	free(ic->mapped_to_output);
+	free(ic->mapped_to_region);
 	free(ic);
 }
 
diff --git a/sway/input/seat.c b/sway/input/seat.c
index dc21ce61..5fc23a19 100644
--- a/sway/input/seat.c
+++ b/sway/input/seat.c
@@ -576,6 +576,7 @@ static void seat_reset_input_config(struct sway_seat *seat,
 static void seat_apply_input_config(struct sway_seat *seat,
 		struct sway_seat_device *sway_device) {
 	const char *mapped_to_output = NULL;
+	struct wlr_box *mapped_to_region = NULL;
 
 	struct input_config *ic = input_device_get_config(
 			sway_device->input_device);
@@ -583,12 +584,31 @@ static void seat_apply_input_config(struct sway_seat *seat,
 		sway_log(SWAY_DEBUG, "Applying input config to %s",
 			sway_device->input_device->identifier);
 
+		// We use an empty string as a marker to clear the mapped_to_output
+		// property, because a NULL set in a handler_context isn't preserved.
+		if (ic->mapped_to_output != NULL && ic->mapped_to_output[0] == '\0') {
+			free(ic->mapped_to_output);
+			ic->mapped_to_output = NULL;
+			wlr_cursor_map_input_to_output(seat->cursor->cursor,
+				sway_device->input_device->wlr_device, NULL);
+		}
+
 		mapped_to_output = ic->mapped_to_output;
+		if (mapped_to_output != NULL) {
+			// Output has just been set, clear region setting.
+			free(ic->mapped_to_region);
+			ic->mapped_to_region = NULL;
+			wlr_cursor_map_input_to_region(seat->cursor->cursor,
+				sway_device->input_device->wlr_device, NULL);
+		}
+
+		mapped_to_region = ic->mapped_to_region;
 	}
 
-	if (mapped_to_output == NULL) {
+	if (mapped_to_output == NULL && mapped_to_region == NULL) {
 		mapped_to_output = sway_device->input_device->wlr_device->output_name;
 	}
+
 	if (mapped_to_output != NULL) {
 		sway_log(SWAY_DEBUG, "Mapping input device %s to output %s",
 			sway_device->input_device->identifier, mapped_to_output);
@@ -604,6 +624,13 @@ static void seat_apply_input_config(struct sway_seat *seat,
 				sway_device->input_device->wlr_device, output->wlr_output);
 			sway_log(SWAY_DEBUG, "Mapped to output %s", output->wlr_output->name);
 		}
+	} else if (mapped_to_region != NULL) {
+		sway_log(SWAY_DEBUG, "Mapping input device %s to %d,%d %dx%d",
+			sway_device->input_device->identifier,
+			mapped_to_region->x, mapped_to_region->y,
+			mapped_to_region->width, mapped_to_region->height);
+		wlr_cursor_map_input_to_region(seat->cursor->cursor,
+			sway_device->input_device->wlr_device, mapped_to_region);
 	}
 }
 
diff --git a/sway/meson.build b/sway/meson.build
index 24628100..8fcf841c 100644
--- a/sway/meson.build
+++ b/sway/meson.build
@@ -150,6 +150,7 @@ sway_sources = files(
 	'commands/input/left_handed.c',
 	'commands/input/map_from_region.c',
 	'commands/input/map_to_output.c',
+	'commands/input/map_to_region.c',
 	'commands/input/middle_emulation.c',
 	'commands/input/natural_scroll.c',
 	'commands/input/pointer_accel.c',
diff --git a/sway/sway-input.5.scd b/sway/sway-input.5.scd
index 2ee95c0b..d0bf648b 100644
--- a/sway/sway-input.5.scd
+++ b/sway/sway-input.5.scd
@@ -88,7 +88,7 @@ The following commands may only be used in the configuration file.
 	Maps inputs from this device to the specified output. Only meaningful if the
 	device is a pointer, touch, or drawing tablet device.
 
-*input* <identifier> map_to_region <WxH@X,Y>
+*input* <identifier> map_to_region <X> <Y> <width> <height>
 	Maps inputs from this device to the specified region of the global output
 	layout. Only meaningful if the device is a pointer, touch, or drawing tablet
 	device.